The putative antigenicepitope was identified on the viral nucleoprotein.
2
Recently, we defined the antigenicepitope recognized by the human monoclonal antibody L94 to be a protein with a C-terminal sequence of alanine-proline (AP).
3
Two amino acid motifs in region I were predicted to contain the common antigenicepitopes.
4
Antigenicepitopes on the 3D structure of these proteins was also predicted using bioinformatics analysis.
5
Immune escape by antigenic drift, in which viruses generate mutations in key antigenicepitopes, becomes highly exaggerated.
Uso de epitope em inglês
1
However, no easily applicable approach for CTL epitope identification has been developed.
2
No robust evidence of immune response to the target epitope was detected.
3
These results reveal the existence of atypical mechanisms of HIV-1 epitope generation.
4
The natural epitope contains a serine residue at P2 of the peptide.
5
T-cell responses were measured against pools of global potential T-cell epitope peptides.
6
The mechanism by which the alpha-galactosyl epitope was reduced was also studied.
7
These experiments identified five distinct epitope clusters on the surface of holo-TC.
8
Evolutionary analysis was combined with homology modeling and T-B cells epitope predictions.
9
The nucleotide sequence encoding this epitope was designed utilizing optimal plant codons.
10
The epitope off-rate was evaluated by gel filtration and T cell-based assays.
11
With synthetic peptides, the epitope was further limited to eight amino acids.
12
Statistical evidence for positive Darwinian selective pressure against an immunodominant epitope is presented.
13
Therefore, the C terminus of the epitope is not properly generated.
14
This may explain the common recognition of this newly discovered epitope.
15
CD8 T-cell epitope regions were defined based on literature data and prediction models.
16
A new T helper epitope in the p6 protein of Gag was identified.